| Long name: |
FITC Conjugated, CYLN2/CLIP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CYLN2/CLIP |
| Specificity: |
This is a highly specific antibody against CYLN2/CLIP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CYLN2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CLIP-115 is a microtubule-binding protein that is abundantly expressed in the brain, In Williams Syndrome patients, Mice with haploinsufficiency for the CYLN2 gene have features similar to that of WS, This region comprises the CYLN2 gene, a heterozygous deletion is present in a region on chromosome 7q11, brain abnormalities, dysmorphic features, hippocampal dysfunction and particular deficits in motor coordination, including mild growth deficiency, mental retardation or learning difficulties and several typical behavioral and neurological abnormalities, which encodes the cytoplasmic linker protein of (CLIP-115), which spans approximately 20 genes, 23 (the Williams Syndrome critical region), Williams Syndrome (WS) is a developmental disorder characterized by cardiovascular problems |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CLIP-115 KIAA0291 WSCR4 CLIP WSCR3 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CYLN2/CLIP Conjugated |
| Short name: |
FITC Conjugated, CYLN2/CLIP Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, CYLN2/CLIP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2586 |
| Gene: |
CLIP2 |
More about : CLIP2 |
| Long gene name: |
CAP-Gly domain containing linker protein 2 |
| Synonyms gene: |
WBSCR4 CYLN2 WBSCR3 |
| Synonyms gene name: |
cytoplasmic linker 2 Williams-Beuren syndrome chromosome region 3 CAP-GLY domain containing linker protein 2 |
| Locus: |
7q11, 23 |
| Discovery year: |
1997-09-12 |
| GenBank acession: |
AB006629 |
| Entrez gene record: |
7461 |
| Pubmed identfication: |
8812460 9799601 |
| RefSeq identity: |
NM_003388 |
| Havana BLAST/BLAT: |
OTTHUMG00000022980 |