| Long name: |
Biotin Conjugated, CYLN2/CLIP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CYLN2/CLIP |
| Specificity: |
This is a highly specific antibody against CYLN2/CLIP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CYLN2 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CLIP-115 is a microtubule-binding protein that is abundantly expressed in the brain, In Williams Syndrome patients, Mice with haploinsufficiency for the CYLN2 gene have features similar to that of WS, This region comprises the CYLN2 gene, a heterozygous deletion is present in a region on chromosome 7q11, brain abnormalities, dysmorphic features, hippocampal dysfunction and particular deficits in motor coordination, including mild growth deficiency, mental retardation or learning difficulties and several typical behavioral and neurological abnormalities, which encodes the cytoplasmic linker protein of (CLIP-115), which spans approximately 20 genes, 23 (the Williams Syndrome critical region), Williams Syndrome (WS) is a developmental disorder characterized by cardiovascular problems |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CLIP-115 KIAA0291 WSCR4 CLIP WSCR3 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CYLN2/CLIP Conjugated |
| Short name: |
Conjugated, CYLN2/CLIP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, CYLN2/CLIP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2586 |
| Gene: |
CLIP2 |
More about : CLIP2 |
| Long gene name: |
CAP-Gly domain containing linker protein 2 |
| Synonyms gene: |
WBSCR4 CYLN2 WBSCR3 |
| Synonyms gene name: |
cytoplasmic linker 2 Williams-Beuren syndrome chromosome region 3 CAP-GLY domain containing linker protein 2 |
| Locus: |
7q11, 23 |
| Discovery year: |
1997-09-12 |
| GenBank acession: |
AB006629 |
| Entrez gene record: |
7461 |
| Pubmed identfication: |
8812460 9799601 |
| RefSeq identity: |
NM_003388 |
| Havana BLAST/BLAT: |
OTTHUMG00000022980 |