| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CYLN2/CLIP |
| Specificity: |
This antibody reacts specifically with CYLN2/CLIP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CYLN2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
CLIP-115 is a microtubule-binding protein that is abundantly expressed in the brain, In Williams Syndrome patients, Mice with haploinsufficiency for the CYLN2 gene have features similar to that of WS, This region comprises the CYLN2 gene, a heterozygous deletion is present in a region on chromosome 7q11, brain abnormalities, dysmorphic features, hippocampal dysfunction and particular deficits in motor coordination, including mild growth deficiency, mental retardation or learning difficulties and several typical behavioral and neurological abnormalities, which encodes the cytoplasmic linker protein of (CLIP-115), which spans approximately 20 genes, 23 (the Williams Syndrome critical region), Williams Syndrome (WS) is a developmental disorder characterized by cardiovascular problems |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CLIP-115 KIAA0291 WSCR4 CLIP WSCR3 |
| Also known as: |
CYLN2/CLIP Polyclonal Antibody |
| Other name: |
Anti-CYLN2/CLIP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CYLN2/CLIP |
| Short name: |
Anti-CYLN2/CLIP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CYLN2/CLIP (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2586 |
| Gene: |
CLIP2 |
More about : CLIP2 |
| Long gene name: |
CAP-Gly domain containing linker protein 2 |
| Synonyms gene: |
WBSCR4 CYLN2 WBSCR3 |
| Synonyms gene name: |
cytoplasmic linker 2 Williams-Beuren syndrome chromosome region 3 CAP-GLY domain containing linker protein 2 |
| Locus: |
7q11, 23 |
| Discovery year: |
1997-09-12 |
| GenBank acession: |
AB006629 |
| Entrez gene record: |
7461 |
| Pubmed identfication: |
8812460 9799601 |
| RefSeq identity: |
NM_003388 |
| Havana BLAST/BLAT: |
OTTHUMG00000022980 |