| Long name: |
Biotin Conjugated, NAB2/MADER Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NAB2/MADER |
| Specificity: |
This is a highly specific antibody against NAB2/MADER |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human NAB2 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Both NAB1 and NAB2 contain an amino terminal NAB conserved domain 1 (NCB1), NAB1 and NAB2 are corepressors of EGF-1/NGFI-A, NAB2 is principally localized in the nucleus and may play a role in the downregulation of NGFI-A activity as well as in controlling fundamental processes such as cell division, NAB2 localizes to chromosome 12q13, The evolutionarily conserved NAB proteins, a region that is rearranged in several solid tumors, and a carboxy terminal NCD2 domain, and coregulatory proteins, and liposarcomas, differentiation and apoptosis, lipomas, such as Egr-1/NGFI-A, such as NAB (for NGFI-A-binding proteins), which is required for binding NGFI-A, which is responsible for the repressor function of NAB proteins, 1, 3-14, Transcriptional control is in part regulated by interactions between DNA-bound transcription factors |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
MADER |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NAB2/MADER Conjugated |
| Short name: |
Conjugated, NAB2/MADER Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, NAB2/MADER (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7627 |
| Gene: |
NAB2 |
More about : NAB2 |
| Long gene name: |
NGFI-A binding protein 2 |
| Synonyms gene name: |
NGFI-A binding protein 2 (EGR1 binding protein 2) |
| Synonyms name: |
EGR1 binding protein 2 |
| Locus: |
12q13, 3 |
| Discovery year: |
1996-10-11 |
| GenBank acession: |
BC065931 |
| Entrez gene record: |
4665 |
| Pubmed identfication: |
8668170 8649813 |
| RefSeq identity: |
NM_005967 |
| Havana BLAST/BLAT: |
OTTHUMG00000171192 |