| Long name: |
NAB2/MADER Primary Polyclonal Antibody |
| Also known as: |
NAB2/MADER PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
NAB2/MADER |
| Specificity: |
This is a highly specific antibody against NAB2/MADER |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NAB2 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Both NAB1 and NAB2 contain an amino terminal NAB conserved domain 1 (NCB1), NAB1 and NAB2 are corepressors of EGF-1/NGFI-A, NAB2 is principally localized in the nucleus and may play a role in the downregulation of NGFI-A activity as well as in controlling fundamental processes such as cell division, NAB2 localizes to chromosome 12q13, The evolutionarily conserved NAB proteins, a region that is rearranged in several solid tumors, and a carboxy terminal NCD2 domain, and coregulatory proteins, and liposarcomas, differentiation and apoptosis, lipomas, such as Egr-1/NGFI-A, such as NAB (for NGFI-A-binding proteins), which is required for binding NGFI-A, which is responsible for the repressor function of NAB proteins, 1, 3-14, Transcriptional control is in part regulated by interactions between DNA-bound transcription factors |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
EGR-1-binding protein 2, EGR1 binding protein 2, MADER, MGC75085, Melanoma associated delayed early response protein, Melanoma-associated delayed early response protein, NAB2_HUMAN, NGFI A binding protein 2, NGFI A binding protein 2 EGR1 binding protein 2, NGFI-A-binding protein 2, Nab 2, Protein MADER, nab2, EGR 1 binding protein 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NAB2/MADER |
| Short name: |
NAB2/MADER Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NAB2/MADER (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7627 |
| Gene: |
NAB2 |
More about : NAB2 |
| Long gene name: |
NGFI-A binding protein 2 |
| Synonyms gene name: |
NGFI-A binding protein 2 (EGR1 binding protein 2) |
| Synonyms: |
MADER |
| Synonyms name: |
EGR1 binding protein 2 |
| Locus: |
12q13, 3 |
| Discovery year: |
1996-10-11 |
| GenBank acession: |
BC065931 |
| Entrez gene record: |
4665 |
| Pubmed identfication: |
8668170 8649813 |
| RefSeq identity: |
NM_005967 |
| Havana BLAST/BLAT: |
OTTHUMG00000171192 |