| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NAB2/MADER |
| Specificity: |
This antibody reacts specifically with NAB2/MADER |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NAB2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Both NAB1 and NAB2 contain an amino terminal NAB conserved domain 1 (NCB1), NAB1 and NAB2 are corepressors of EGF-1/NGFI-A, NAB2 is principally localized in the nucleus and may play a role in the downregulation of NGFI-A activity as well as in controlling fundamental processes such as cell division, NAB2 localizes to chromosome 12q13, The evolutionarily conserved NAB proteins, a region that is rearranged in several solid tumors, and a carboxy terminal NCD2 domain, and coregulatory proteins, and liposarcomas, differentiation and apoptosis, lipomas, such as Egr-1/NGFI-A, such as NAB (for NGFI-A-binding proteins), which is required for binding NGFI-A, which is responsible for the repressor function of NAB proteins, 1, 3-14, Transcriptional control is in part regulated by interactions between DNA-bound transcription factors |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MADER |
| Also known as: |
NAB2/MADER Polyclonal Antibody |
| Other name: |
Anti-NAB2/MADER Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NAB2/MADER |
| Short name: |
Anti-NAB2/MADER (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NAB2/MADER (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
7627 |
| Gene: |
NAB2 |
More about : NAB2 |
| Long gene name: |
NGFI-A binding protein 2 |
| Synonyms gene name: |
NGFI-A binding protein 2 (EGR1 binding protein 2) |
| Synonyms name: |
EGR1 binding protein 2 |
| Locus: |
12q13, 3 |
| Discovery year: |
1996-10-11 |
| GenBank acession: |
BC065931 |
| Entrez gene record: |
4665 |
| Pubmed identfication: |
8668170 8649813 |
| RefSeq identity: |
NM_005967 |
| Havana BLAST/BLAT: |
OTTHUMG00000171192 |