| Long name: |
FITC Conjugated, HSPABP/HIP/HSC70 Interacting Protein HIP Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HSPABP/HIP/HSC70 Interacting Protein HIP |
| Specificity: |
This is a highly specific antibody against HSPABP/HIP/HSC70 Interacting Protein HIP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human HSPABP |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
By collaborating with other positive co-factors such as HSP40 and Hop, Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3), Hip may facilitate the chaperone function of HSP70 in protein folding and repair, The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70, also known as ST13 (suppression of tumorigenicity protein 13), and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1, or competing with negative co-factors such as Bag1, 2), Hip (HSP70-interacting protein) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
HSC71 HSC70 HSP73 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HSPABP/HIP/HSC70 Interacting Protein HIP Conjugated |
| Short name: |
FITC Conjugated, HSPABP/HIP/HSC70 Interacting Protein HIP Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, HSPABP/HIP/HSC70 Interacting Protein HIP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5241 |
| Gene: |
HSPA8 |
More about : HSPA8 |
| Long gene name: |
heat shock protein family A (Hsp70) member 8 |
| Synonyms gene: |
HSPA10 |
| Synonyms gene name: |
heat shock 70kD protein 8 heat shock 70kDa protein 8 |
| Locus: |
11q24, 1 |
| Discovery year: |
1995-05-08 |
| GenBank acession: |
Y00371 |
| Entrez gene record: |
3312 |
| Pubmed identfication: |
8530083 3037489 |
| Classification: |
NineTeen complex Heat shock 70kDa proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000166030 |