| Long name: |
HSPABP/HIP/HSC70 Interacting Protein HIP Antibody |
| Also known as: |
HSPABP/HIP/HSC70 Interacting Protein HIP Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
HSPABP/HIP/HSC70 Interacting Protein HIP |
| Specificity: |
This is a highly specific antibody against HSPABP/HIP/HSC70 Interacting Protein HIP |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HSPABP |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
By collaborating with other positive co-factors such as HSP40 and Hop, Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3), Hip may facilitate the chaperone function of HSP70 in protein folding and repair, The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70, also known as ST13 (suppression of tumorigenicity protein 13), and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1, or competing with negative co-factors such as Bag1, 2), Hip (HSP70-interacting protein) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AAG2, Aging associated protein 2, F10A1_HUMAN, FAM10A1, FAM10A4, FLJ27260, HIP, HOP, HSPABP, HSPABP 1, HSPABP1, Heat shock 70kD protein binding protein, Hsc70 interacting protein, Hsc70-interacting protein, Hsp70 interacting protein, MGC129952, OTTHUMP00000028873, P48 antibody PRO0786, Progesterone receptor associated p48 protein, Progesterone receptor-associated p48 protein, Protein FAM10A1, Putative tumor suppressor ST13, Renal carcinoma antigen NY REN 33, Renal carcinoma antigen NY-REN-33, SNC 6, SNC6, ST 13, ST13, Suppression of tumorigenicity 13, Suppression of tumorigenicity 13 colon carcinoma, Suppression of tumorigenicity 13 protein, Suppression of tumorigenicity protein 13, AAG 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HSPABP/HIP/HSC70 Interacting Protein HIP |
| Short name: |
HSPABP/HIP/HSC70 Interacting Protein HIP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HSPABP/HIP/HSC70 Interacting Protein HIP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5241 |
| Gene: |
HSPA8 |
More about : HSPA8 |
| Long gene name: |
heat shock protein family A (Hsp70) member 8 |
| Synonyms gene: |
HSPA10 |
| Synonyms gene name: |
heat shock 70kD protein 8 heat shock 70kDa protein 8 |
| Synonyms: |
HSC71 HSC70 HSP73 |
| Locus: |
11q24, 1 |
| Discovery year: |
1995-05-08 |
| GenBank acession: |
Y00371 |
| Entrez gene record: |
3312 |
| Pubmed identfication: |
8530083 3037489 |
| Classification: |
NineTeen complex Heat shock 70kDa proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000166030 |