| Long name: |
Biotin Conjugated, PIST/GOPC Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PIST/GOPC |
| Specificity: |
This is a highly specific antibody against PIST/GOPC |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human PIST |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Additionally, CAL or FIG, Chromosomal aberrations in the gene encoding PIST are found in glioblastoma multiform (GBM), Expressed ubiquitously and containing one PDZ (DHR) domain, PIST functions as a homooligomer that interacts with a variety of proteins and plays a role in intracellular protein trafficking and degradation, PIST is thought to regulate ionic currents via membrane channel modification and may also play a role in autophagy, Three isoforms of PIST exist due to alternative splicing events, a common and aggressive form of brain tumor, also known as GOPC (golgi associated PDZ and coiled-coil motif containing), as well as to the membrane of the golgi apparatus and to the cell junction, is a 462 amino acid protein that localizes to the cytoplasm, suggesting a role for mutated PIST in carcinogenesis, PIST (PDZ protein interacting specifically with TC10) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
dJ94G16, 2 PIST FIG GOPC1 CAL |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PIST/GOPC Conjugated |
| Short name: |
Conjugated, PIST/GOPC Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, PIST/GOPC (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17643 |
| Gene: |
GOPC |
More about : GOPC |
| Long gene name: |
golgi associated PDZ and coiled-coil motif containing |
| Locus: |
6q22, 1 |
| Discovery year: |
2003-08-29 |
| GenBank acession: |
AF287894 |
| Entrez gene record: |
57120 |
| Pubmed identfication: |
11162552 11520064 |
| RefSeq identity: |
NM_020399 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000015457 |