| Long name: |
PIST/GOPC Primary Polyclonal Antibody |
| Also known as: |
PIST/GOPC PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PIST/GOPC |
| Specificity: |
This is a highly specific antibody against PIST/GOPC |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PIST |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Additionally, CAL or FIG, Chromosomal aberrations in the gene encoding PIST are found in glioblastoma multiform (GBM), Expressed ubiquitously and containing one PDZ (DHR) domain, PIST functions as a homooligomer that interacts with a variety of proteins and plays a role in intracellular protein trafficking and degradation, PIST is thought to regulate ionic currents via membrane channel modification and may also play a role in autophagy, Three isoforms of PIST exist due to alternative splicing events, a common and aggressive form of brain tumor, also known as GOPC (golgi associated PDZ and coiled-coil motif containing), as well as to the membrane of the golgi apparatus and to the cell junction, is a 462 amino acid protein that localizes to the cytoplasm, suggesting a role for mutated PIST in carcinogenesis, PIST (PDZ protein interacting specifically with TC10) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CFTR associated ligand, CFTR-associated ligand, FIG, Fused in glioblastoma, GOPC, GOPC1, GOPC_HUMAN, Golgi associated PDZ and coiled coil mot containing, Golgi associated PDZ and coiled coil mot containing protein, Golgi-associated PDZ and coiled-coil mot-containing protein, OTTHUMP00000040403, PDZ protein interacting specically with TC 10, PDZ protein interacting specically with TC10, PDZ/coiled coil domain binding partner for the rho family GTPase TC 10, PDZ/coiled coil domain binding partner for the rho family GTPase TC10, PIST, Protein interacting specically with Tc 10, Protein interacting specically with Tc10, dJ94G16, dJ94G16, 2, 2 PIST, CAL |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PIST/GOPC |
| Short name: |
PIST/GOPC Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PIST/GOPC (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17643 |
| Gene: |
GOPC |
More about : GOPC |
| Long gene name: |
golgi associated PDZ and coiled-coil motif containing |
| Synonyms: |
dJ94G16, 2 PIST FIG GOPC1 CAL |
| Locus: |
6q22, 1 |
| Discovery year: |
2003-08-29 |
| GenBank acession: |
AF287894 |
| Entrez gene record: |
57120 |
| Pubmed identfication: |
11162552 11520064 |
| RefSeq identity: |
NM_020399 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000015457 |