| Long name: |
ALEXA FLUOR 647 Conjugated, Sema4C Polyclonal Antibody |
| Also known as: |
Anti-Sema4C PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Sema4C |
| Specificity: |
This is a highly specific antibody against Sema4C |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Sema4C |
| Gene ID Number: |
9037 |
| Swiss Prot: |
Q13591 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
In glioma cells, Ligand for receptor PLXNB3, May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1, while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity), Bifunctional axonal guidance cue regulated by sulfated proteoglycans |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
Semacl1 Semaf |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Sema4C Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Sema4C |
| Short name: |
Sema4C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
(semaphorin) 4C (Antibody to), ALEXA FLUOR 647, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, sema domain |
| Alternative technique: |
antibodies |
| Identity: |
10731 |
| Gene: |
SEMA4C |
More about : SEMA4C |
| Long gene name: |
semaphorin 4C |
| Synonyms gene: |
SEMAI |
| Synonyms gene name: |
(semaphorin) 4C , immunoglobulin domain (Ig), sema domain, transmembrane domain (TM) and short cytoplasmic domain |
| Synonyms name: |
M-Sema F |
| Locus: |
2q11, 2 |
| Discovery year: |
2004-02-04 |
| GenBank acession: |
AB051526 |
| Entrez gene record: |
54910 |
| Pubmed identfication: |
7656991 |
| RefSeq identity: |
NM_017789 |
| Classification: |
Semaphorins Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130535 |