| Long name: |
Sema4C Primary Polyclonal Antibody |
| Also known as: |
Sema4C PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Sema4C |
| Specificity: |
This is a highly specific antibody against Sema4C |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Sema4C |
| Gene ID number: |
9037 |
| Swiss Prot: |
Q13591 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
In glioma cells, Ligand for receptor PLXNB3, May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1, while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity), Bifunctional axonal guidance cue regulated by sulfated proteoglycans |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
SEMA5A, SEMAF, Sema F, Semaphorin-5A, Semaphorin-F, semF |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Sema4C |
| Short name: |
Sema4C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
(semaphorin) 4C (Antibody to), immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, sema domain |
| Alternative technique: |
antibodies |
| Identity: |
10731 |
| Gene: |
SEMA4C |
More about : SEMA4C |
| Long gene name: |
semaphorin 4C |
| Synonyms gene: |
SEMAI |
| Synonyms gene name: |
(semaphorin) 4C , immunoglobulin domain (Ig), sema domain, transmembrane domain (TM) and short cytoplasmic domain |
| Synonyms: |
Semacl1 Semaf |
| Synonyms name: |
M-Sema F |
| Locus: |
2q11, 2 |
| Discovery year: |
2004-02-04 |
| GenBank acession: |
AB051526 |
| Entrez gene record: |
54910 |
| Pubmed identfication: |
7656991 |
| RefSeq identity: |
NM_017789 |
| Classification: |
Semaphorins Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130535 |