NSMase2 Antibody, ALEXA FLUOR 488

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Catalog number: bs-11193R-A488
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: NSMase2 Antibody, ALEXA FLUOR 488
Quantity: 100ul
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Long name: ALEXA FLUOR 488 Conjugated, NSMase2 Polyclonal Antibody
Also known as: Anti-NSMase2 PAb ALEXA FLUOR 488
Category: Conjugated Primary Antibodies
Conjugated with: 488, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: NSMase2
Specificity: This is a highly specific antibody against NSMase2
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NSMase2
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: Expression of N-SMase2 is upregulated during the G0/G1 phases of the cell cycle and optimal N-SMase2 activity occurs at a slightly basic pH of 7, Localized to the membrane of the Golgi apparatus, N-SMase2 deficiency is the cause of chondrodysplasia, N-SMase2 functions to catalyze the hydrolysis of sphingomyelin to form ceramide and phosphocholineâ, N-SMase2 is enzymatically activated by unsaturated fatty acids and phosphatidylserine and, a genetic disorder characterized by impaired bone growth that leads to short stature, also known as NSMASE2 or SMPD3 (sphingomyelin phosphodiesterase 3), bowlegs and underdeveloped joints, is a ubiquitously expressed 655 amino acid member of the magnesium-dependent phosphohydrolase protein family, is involved in growth suppression and postnatal development, through regulation of ceramide synthesis, &euro, &rdquo, 5, N-SMase2 (neutral sphingomyelinase 2), two proteins that mediate cell growth arrest and apoptosis
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 499nm/519nm
Synonyms: NSMASE2
Properties: ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the NSMase2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Gene target: NSMase2
Short name: NSMase2 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 488
Alternative name: ALEXA FLUOR 488, NSMase2 (Antibody to)
Alternative technique: antibodies
Identity: 14240
Gene: SMPD3 | More about : SMPD3
Long gene name: sphingomyelin phosphodiesterase 3
Synonyms gene name: neutral membrane (neutral sphingomyelinase II) , sphingomyelin phosphodiesterase 3
Synonyms name: neutral sphingomyelinase II
Locus: 16q22, 1
Discovery year: 2000-12-12
GenBank acession: AJ250460
Entrez gene record: 55512
Pubmed identfication: 10823942
RefSeq identity: NM_018667
Havana BLAST/BLAT: OTTHUMG00000137559

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