| Long name: |
Biotin Conjugated, Neurexin 2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Neurexin 2 |
| Specificity: |
This is a highly specific antibody against Neurexin 2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human Neurexin 2 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Caspr (for Contactin-Associated Protein 1, Caspr and the closely related Caspr2, Caspr exists at the paranodal junctions, Caspr may play a role in the communication of glial cells and neurons during development, Neurexins, Neurexins I-III are expressed as a and b isoforms, Sex hormone-binding)-domains separated by EGF domains, Specifically, The a isoforms are made of three cassettes, The a isoforms bind to neurexophilins at the second LNS site and to the excitatory neurotoxin a-latrotoxin, The b isoforms have only one LNS-domain, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), also designated Paranodin in mouse), and binds to the surface glycoprotein Contactin, and play a role in the formation and remodeling of synapes, bind to neuroligins, contains an extracellular domain similar to the other three neurexins, demarcate distinct subdomains in myelinated axons, followed by a transmembrane region and a 55 amino acid cytoplasmic C-terminal, neurexin II (NRXN2), neurexin III (NRXN3) and Caspr (neurexin IV), which contain two LNS (Laminin A, which include neurexin I (NRXN1), while Caspr2 colocalizes with Shaker-like K+ channels in the juxtaparanodal region, Neurexins comprise a family of neuronal cell surface proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
NRX2A_HUMAN, NRXN 2, NRXN-2, NRXN2, Neurexin II, Neurexin II alpha, Neurexin-2, Neurexin2, Neurexin 2 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Neurexin 2 Conjugated |
| Short name: |
Conjugated, Neurexin 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Neurexin 2 (Antibody to) |
| Alternative technique: |
antibodies |