| Long name: |
Neurexin 1 Primary Polyclonal Antibody |
| Also known as: |
Neurexin 1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Neurexin 1 |
| Specificity: |
This is a highly specific antibody against Neurexin 1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
40-90/1477 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Neurexin 1 |
| Gene ID number: |
9378 |
| Swiss Prot: |
Q9ULB1 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Caspr (for Contactin-Associated Protein 1, Caspr and the closely related Caspr2, Caspr exists at the paranodal junctions, Caspr may play a role in the communication of glial cells and neurons during development, Neurexins, Neurexins I-III are expressed as a and b isoforms, Sex hormone-binding)-domains separated by EGF domains, Specifically, The a isoforms are made of three cassettes, The a isoforms bind to neurexophilins at the second LNS site and to the excitatory neurotoxin a-latrotoxin, The b isoforms have only one LNS-domain, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), also designated Paranodin in mouse), and binds to the surface glycoprotein Contactin, and play a role in the formation and remodeling of synapes, bind to neuroligins, contains an extracellular domain similar to the other three neurexins, demarcate distinct subdomains in myelinated axons, followed by a transmembrane region and a 55 amino acid cytoplasmic C-terminal, neurexin II (NRXN2), neurexin III (NRXN3) and Caspr (neurexin IV), which contain two LNS (Laminin A, which include neurexin I (NRXN1), while Caspr2 colocalizes with Shaker-like K+ channels in the juxtaparanodal region, Neurexins comprise a family of neuronal cell surface proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
NRX1A_HUMAN, NRXN1, Neurexin 1 beta, Neurexin I-alpha, Neurexin-1-alpha, PTHSL2, Neurexin 1 alpha |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Neurexin 1 |
| Short name: |
Neurexin 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Neurexin 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8008 |
| Gene: |
NRXN1 |
More about : NRXN1 |
| Long gene name: |
neurexin 1 |
| Synonyms: |
KIAA0578 Hs, 22998 |
| Locus: |
2p16, 3 |
| Discovery year: |
1998-10-14 |
| GenBank acession: |
AB011150 |
| Entrez gene record: |
9378 |
| RefSeq identity: |
NM_001135659 |
| Havana BLAST/BLAT: |
OTTHUMG00000129263 |