| Long name: |
FITC Conjugated, Neurexin 1 beta Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Neurexin 1 beta |
| Specificity: |
This antibody will detect Neurexin 1 and Neurexin 1 beta, This is a highly specific antibody against Neurexin 1 beta |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
280-330/442 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human Neurexin 1 beta |
| Gene ID number: |
9378 |
| Swiss Prot: |
Q9ULB1 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission, Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions, Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (By similarity), Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their calcium-dependent interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2, Function is isoform-specific, In vitro, Likewise, May be involved in specification of excitatory synapses, They may effect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery, They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland, a subtype of glutamate-gated ion channels, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, exocytosis of secretory granules and regulation of signal transmission, triggers the de novo formation of presynaptic structures, Cell surface protein involved in cell-cell-interactions |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
Hs, KIAA0578, NRXN1, Neurexin I-alpha, Neurexin-1, Neurexin-1-alpha, SCZD17, 22998, PTHSL2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Neurexin 1 beta Conjugated |
| Short name: |
FITC Conjugated, Neurexin 1 beta Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Neurexin 1 b (Antibody to) |
| Alternative technique: |
antibodies |