| Long name: |
FITC Conjugated, Bestrophin 2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Bestrophin 2 |
| Specificity: |
This is a highly specific antibody against Bestrophin 2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Bestrophin 2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
1 also known as Best disease, 3 and 4, Bestrophin 2, Bestrophins were originally defined as a family of over 20 related sequences of the C, Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels, It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac), PR65, RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon, Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein, Three more members of the bestrophin family members were cloned and indentified recently, elegans, was confirmed by reciprocal immunoprecipitation, The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
BEST2, BEST2_HUMAN, Best disease Bestrophin, Bestrophin2, FLJ20132, VMD2, VMD2 like gene 1, VMD2L1, Vitellorm macular dystrophy, Vitellorm macular dystrophy 2 homolog, Vitellorm macular dystrophy 2 like 1, Vitellorm macular dystrophy 2 like protein 1, BEST 2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Bestrophin 2 Conjugated |
| Short name: |
FITC Conjugated, Bestrophin 2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Bestrophin 2 (Antibody to) |
| Alternative technique: |
antibodies |