| Long name: |
Biotin Conjugated, Bestrophin Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Bestrophin |
| Specificity: |
This is a highly specific antibody against Bestrophin |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Bestrophin |
| Gene ID number: |
5068 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Best disease is frequently a reflection of mutations in the Bestrophin gene, Bestrophin Bestrophin 2, Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium, Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision, known as Best disease, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells, Best vitelliform macular dystrophy, Bestrophin 3 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
BEST, BEST-1, BEST1, BEST1, BEST1_HUMAN, BMD, Best macular dystrophy, Bestrophin 1, Bestrophin-1, Bestrophin1, TU15B, VMD 2, VMD2, Vitellorm macular dystrophy, Vitellorm macular dystrophy 2, Vitellorm macular dystrophy protein 2, mBest1, BEST 1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Bestrophin Conjugated |
| Short name: |
Conjugated, Bestrophin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Bestrophin (Antibody to) |
| Alternative technique: |
antibodies |