| Long name: |
Cy3 Conjugated, Bestrophin 2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Bestrophin 2 |
| Specificity: |
This is a highly specific antibody against Bestrophin 2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Bestrophin 2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
1 also known as Best disease, 3 and 4, Bestrophin 2, Bestrophins were originally defined as a family of over 20 related sequences of the C, Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels, It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac), PR65, RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon, Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein, Three more members of the bestrophin family members were cloned and indentified recently, elegans, was confirmed by reciprocal immunoprecipitation, The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
BEST2, BEST2_HUMAN, Best disease Bestrophin, Bestrophin2, FLJ20132, VMD2, VMD2 like gene 1, VMD2L1, Vitellorm macular dystrophy, Vitellorm macular dystrophy 2 homolog, Vitellorm macular dystrophy 2 like 1, Vitellorm macular dystrophy 2 like protein 1, BEST 2 |
| Properties: |
1 of the Bestrophin 2 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Bestrophin 2 Conjugated |
| Short name: |
Conjugated, Bestrophin 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, Bestrophin 2 (Antibody to) |
| Alternative technique: |
antibodies |