| Long name: |
Neurexin 1 beta Primary Polyclonal Antibody |
| Also known as: |
Neurexin 1 beta PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Neurexin 1 beta |
| Specificity: |
This antibody will detect Neurexin 1 and Neurexin 1 beta, This is a highly specific antibody against Neurexin 1 beta |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
280-330/442 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Neurexin 1 beta |
| Gene ID number: |
9378 |
| Swiss Prot: |
Q9ULB1 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission, Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions, Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (By similarity), Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their calcium-dependent interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2, Function is isoform-specific, In vitro, Likewise, May be involved in specification of excitatory synapses, They may effect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery, They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland, a subtype of glutamate-gated ion channels, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, exocytosis of secretory granules and regulation of signal transmission, triggers the de novo formation of presynaptic structures, Cell surface protein involved in cell-cell-interactions |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Hs, KIAA0578, NRXN1, Neurexin I-alpha, Neurexin-1, Neurexin-1-alpha, SCZD17, 22998, PTHSL2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Neurexin 1 beta |
| Short name: |
Neurexin 1 beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Neurexin 1 b (Antibody to) |
| Alternative technique: |
antibodies |