Gliomedin Antibody, ALEXA FLUOR 488

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Catalog number: bs-11032R-A488
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: Gliomedin Antibody, ALEXA FLUOR 488
Quantity: 100ul
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Long name: ALEXA FLUOR 488 Conjugated, Gliomedin Polyclonal Antibody
Also known as: Anti-Gliomedin PAb ALEXA FLUOR 488
Category: Conjugated Primary Antibodies
Conjugated with: 488, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: Gliomedin
Specificity: This is a highly specific antibody against Gliomedin
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Subcellular location: Extracellular
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Gliomedin/COLM
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: Accumulation of Na+ channels at the nodes of Ranvier is a prerequisite for saltatory conduction, Gliomedin is a glial ligand for Neurofascin and NrCAM, Gliomedin is a single-pass type II membrane protein localized to the nodes of Ranvier and is specifically expressed in spinal cord, Gliomedin is expressed by myelinating Schwann cells and accumulates at the edges of each myelin segment during development, Gliomedin is thought to play a role in the formation of the nodes of Ranvier along myelinated axons, In peripheral nerves, It is more abundant in peripheral than central nervous system, brain, clustering of these channels along the axolemma is regulated by myelinating Schwann cells through an unknown mechanism, placenta and sciatic nerve, two axonal immunoglobulin cell adhesion molecules that are associated with Na+ channels at the nodes of Ranvier, where it aligns with the forming nodes, Gliomedin is a 551 amino acid protein encoded by the human gene GLDN
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 499nm/519nm
Synonyms: CRG-L2 CLOM colmedin UNC-112
Properties: ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Gliomedin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Gene target: Gliomedin
Short name: Gliomedin Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 488
Alternative name: ALEXA FLUOR 488, Gliomedin (Antibody to)
Alternative technique: antibodies
Identity: 29514
Gene: GLDN | More about : GLDN
Long gene name: gliomedin
Synonyms gene: COLM
Synonyms gene name: collomin
Locus: 15q21, 2
Discovery year: 2004-05-18
GenBank acession: AY358144
Entrez gene record: 342035
Pubmed identfication: 16039564 12642876
RefSeq identity: NM_181789
Havana BLAST/BLAT: OTTHUMG00000131746

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