| Long name: |
Cy3 Conjugated, SKP2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SKP2 |
| Specificity: |
This is a highly specific antibody against SKP2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
383-424/424 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human Skp2 |
| Gene ID number: |
6502 |
| Swiss Prot: |
Q13309 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CDK9, CDT1, Degradation of CDKN1B/p27kip also requires CKS1, Degradation of TAL1 also requires STUB1, FOXO1, KMT2A/MLL1, Promotes ubiquitination and destruction of CDH1 in a CK1-Dependent Manner, RAG2, RBL2, Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2, Recognizes target proteins ORC1, Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition, TOB1 and TAL1, UBP43, and probably MYC, signal transduction and transcription, thereby regulating cell migration, Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
FBXL1 FBL1 p45 |
| Properties: |
1 of the SKP2 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SKP2 Conjugated |
| Short name: |
Conjugated, SKP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, SKP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10901 |
| Gene: |
SKP2 |
More about : SKP2 |
| Long gene name: |
S-phase kinase associated protein 2 |
| Synonyms gene name: |
E3 ubiquitin protein ligase , S-phase kinase-associated protein 2 (p45) S-phase kinase-associated protein 2 |
| Locus: |
5p13, 2 |
| Discovery year: |
1995-12-18 |
| GenBank acession: |
U33761 |
| Entrez gene record: |
6502 |
| Pubmed identfication: |
8646875 |
| RefSeq identity: |
NM_005983 |
| Classification: |
F-box and leucine rich repeat proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000131106 |