| Long name: |
Biotin Conjugated, SKP2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SKP2 |
| Specificity: |
This is a highly specific antibody against SKP2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
383-424/424 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human Skp2 |
| Gene ID number: |
6502 |
| Swiss Prot: |
Q13309 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CDK9, CDT1, Degradation of CDKN1B/p27kip also requires CKS1, Degradation of TAL1 also requires STUB1, FOXO1, KMT2A/MLL1, Promotes ubiquitination and destruction of CDH1 in a CK1-Dependent Manner, RAG2, RBL2, Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2, Recognizes target proteins ORC1, Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition, TOB1 and TAL1, UBP43, and probably MYC, signal transduction and transcription, thereby regulating cell migration, Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
FBXL1 FBL1 p45 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SKP2 Conjugated |
| Short name: |
Conjugated, SKP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, SKP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10901 |
| Gene: |
SKP2 |
More about : SKP2 |
| Long gene name: |
S-phase kinase associated protein 2 |
| Synonyms gene name: |
E3 ubiquitin protein ligase , S-phase kinase-associated protein 2 (p45) S-phase kinase-associated protein 2 |
| Locus: |
5p13, 2 |
| Discovery year: |
1995-12-18 |
| GenBank acession: |
U33761 |
| Entrez gene record: |
6502 |
| Pubmed identfication: |
8646875 |
| RefSeq identity: |
NM_005983 |
| Classification: |
F-box and leucine rich repeat proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000131106 |