| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SKP2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, FACS, WB |
| Recommended dilutions: |
Flow Cytometry: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the SKP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This SKP2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q13309 |
| Purity: |
Purified |
| Description: |
Fbls containing leucine-rich repeats, In addition, It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), The protein encoded by this gene belongs to the Fbls class, This protein is an essential element of the cyclin A-CDK2 S-phase kinase, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19), and Fbxs containing either different protein-protein interaction modules or no recognizable motifs, in addition to an F-box, the F-box, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas, this protein contains 10 tandem leucine-rich repeats, which function in phosphorylation-dependent ubiquitination, SKP2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif |
| Immunogen: |
A portion of amino acids 156-185 from the human protein was used as the immunogen for this SKP2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SKP2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SKP2 |
| Short name: |
SKP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SKP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10901 |
| Gene: |
SKP2 |
More about : SKP2 |
| Long gene name: |
S-phase kinase associated protein 2 |
| Synonyms gene name: |
E3 ubiquitin protein ligase , S-phase kinase-associated protein 2 (p45) S-phase kinase-associated protein 2 |
| Synonyms: |
FBXL1 FBL1 p45 |
| Locus: |
5p13, 2 |
| Discovery year: |
1995-12-18 |
| GenBank acession: |
U33761 |
| Entrez gene record: |
6502 |
| Pubmed identfication: |
8646875 |
| RefSeq identity: |
NM_005983 |
| Classification: |
F-box and leucine rich repeat proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000131106 |