| Catalog number: | bs-10900R-Biotin |
|---|---|
| Price: | 602 € |
| Supplier: | genways |
| Product name: | GAPDH Polyconal Antibody, Biotin Conjugated |
| Quantity: | 1 tube |
| Related search: |
| Long name: | Biotin Conjugated, GAPDH Polyconal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Biotinylated |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | GAPDH |
| Specificity: | This is a highly specific antibody against GAPDH |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | Recombinant full length human GAPDH |
| Gene ID number: | 2597 |
| Swiss Prot: | P04406 |
| Tested applications: | WB |
| Recommended dilutions: | WB(1:100-1000) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes, DNA replication and apoptosis, Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity), Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate, HDAC2 and PRKDC, Modulates the organization and assembly of the cytoskeleton, Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, Participates in nuclear events including transcription, RNA transport, Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation, respectively, thereby playing a role in glycolysis and nuclear functions, Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | GAPDH Polyconal Conjugated |
| Short name: | Conjugated, GAPDH Polyconal Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Biotin |
| Alternative name: | biotinilated coupled, GAPDH Polyconal (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 4141 |
| Gene: | GAPDH | More about : GAPDH |
| Long gene name: | glyceraldehyde-3-phosphate dehydrogenase |
| Synonyms gene: | GAPD |
| Locus: | 12p13, 31 |
| Discovery year: | 2001-06-22 |
| GenBank acession: | AF261085 |
| Entrez gene record: | 2597 |
| Pubmed identfication: | 3170585 |
| RefSeq identity: | NM_002046 |
| Havana BLAST/BLAT: | OTTHUMG00000137379 |
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