| Catalog number: | bs-10900R |
|---|---|
| Price: | 732 € |
| Supplier: | acr |
| Product name: | GAPDH Polyconal Antibody |
| Quantity: | 50 Вµg |
| Related search: |
| Long name: | GAPDH Polyconal Antibody |
|---|---|
| Also known as: | GAPDH Polyconal Antibody |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | GAPDH |
| Specificity: | This is a highly specific antibody against GAPDH |
| Modification(s): | None |
| Modification site(s): | Unmodified antibody |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | Recombinant full length human GAPDH |
| Gene ID number: | 2597 |
| Swiss Prot: | P04406 |
| Tested Applications: | WB |
| Recommended dilutions: | WB(1:100-1000) |
| Cross reactivity: | Mouse, Rat, Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes, DNA replication and apoptosis, Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity), Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate, HDAC2 and PRKDC, Modulates the organization and assembly of the cytoskeleton, Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, Participates in nuclear events including transcription, RNA transport, Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation, respectively, thereby playing a role in glycolysis and nuclear functions, Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | CDABP0047, GAPD, GAPDH, OK/SW-cl, Peptidyl-cysteine S-nitrosylase GAPDH, 12, Glyceraldehyde-3-phosphate dehydrogenase |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | GAPDH Polyconal |
| Short name: | GAPDH Polyconal Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | GAPDH Polyconal (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 4141 |
| Gene: | GAPDH | More about : GAPDH |
| Long gene name: | glyceraldehyde-3-phosphate dehydrogenase |
| Synonyms gene: | GAPD |
| Locus: | 12p13, 31 |
| Discovery year: | 2001-06-22 |
| GenBank acession: | AF261085 |
| Entrez gene record: | 2597 |
| Pubmed identfication: | 3170585 |
| RefSeq identity: | NM_002046 |
| Havana BLAST/BLAT: | OTTHUMG00000137379 |
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