| Catalog number: | bs-10484R-A594 |
|---|---|
| Price: | 520 € |
| Supplier: | MBS Polyclonals |
| Product name: | Heparanase Antibody, ALEXA FLUOR 594 |
| Quantity: | 100ug |
| Other quantities: | 100ul 332€ |
| Related search: |
| Long name: | ALEXA FLUOR 594 Conjugated, Heparanase Polyclonal Antibody |
|---|---|
| Also known as: | Anti-Heparanase PAb ALEXA FLUOR 594 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 594, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | Heparanase |
| Specificity: | This is a highly specific antibody against Heparanase |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Heparanase |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Heparanase is a heterodimer comprised of a 50 kDa subunit harboring the active site and an 8 kDa subunit, Heparanase is highly expressed in myeloid leukocytes (i, Heparanase plays an important role in ECM degradation, Human heparanase was found to be upregulated in various types of primary tumors, It is produced as a latent 65 kDa precursor and proteolytically processed to its active form, Upon degradation, correlating in some cases with increased tumor invasiveness and vascularity and with poor prospective survival, facilitating the migration and extravasations of tumor cells and inflammatory leukocytes, heparanase releases growth factors and cytokines that stimulate cell proliferation and chemotaxis, neutrophils) in platelets and in human placenta, which degrades heparan sulfate side chains of heparan sulfate proteoglycans (HSPGs) in the extracellular matrix, Heparanase is an endo-beta-D-glucuronidase, e |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 590nm/617nm |
| Synonyms: | HPA2 HPR2 HPSE2 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: | Alexa conjugate 1 |
| Gene target: | Heparanase |
| Short name: | Heparanase Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 594 |
| Alternative name: | ALEXA FLUOR 594, Heparanase (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 12521 |
| Gene: | UFS | More about : UFS |
| Long gene name: | heparanase 2 (inactive) |
| Synonyms gene name: | urofacial syndrome heparanase 2 |
| Locus: | 10q24, 2 |
| Discovery year: | 2002-09-02 |
| GenBank acession: | AF282885 |
| Entrez gene record: | 60495 |
| Pubmed identfication: | 11027606 20560210 9199567 20576607 |
| RefSeq identity: | NM_021828 |
| Havana BLAST/BLAT: | OTTHUMG00000018880 |
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