| Long name: |
Factor VIII B chain Primary Polyclonal Antibody |
| Also known as: |
Factor VIII B chain PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Factor VIII B chain |
| Specificity: |
This is a highly specific antibody against Factor VIII B chain |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Factor VIII B chain |
| Gene ID number: |
2157 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Defects in this gene results in hemophilia A, Jul 2008], This binding domain is essential for coagulant activity, This gene produces two alternatively spliced transcripts, This protein undergoes multiple cleavage events, Transcript variant 1 encodes a large glycoprotein, Transcript variant 2 encodes a putative small protein, [provided by RefSeq, a common recessive X-linked coagulation disorder, converts factor X to the activated form Xa, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, isoform a, isoform b, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex, which consists primarily of the phospholipid binding domain of factor VIIIc, which participates in the intrinsic pathway of blood coagulation, This gene encodes coagulation factor VIII |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
200 kDa isoform, 92 kDa isoform, AHF, Ahf, Antihemophilic factor, Coagulation factor VIII, Coagulation factor VIII associated protein b, Coagulation factor VIII isoform b, Coagulation factor VIII procoagulent component, Coagulation factor VIIIc, DXS1253E, Dna segment on chromosome x unique 1253 expressed sequence, Dxs1253e, Fâ, F8, F8 protein, F8B, F8C, F8b, F8c, FA8_HUMAN, FVIII, FVIII, Factor VIII B chain, Factor VIII F8b, Factor VIIIa heavy chain, Factor VIIIa heavy chain, FactorVIII, HEMA, Hema coagulation factor VIIIc procoagulent component, Hemophilia a, Hemophilia classic, OTTHUMP00000061446, Procoagulant component, &hellip, §, -Ag, coagulation factor VIII |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Factor VIII B chain |
| Short name: |
Factor VIII B chain Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Factor VIII B epitope (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2294 |
| Gene: |
COX8A |
More about : COX8A |
| Long gene name: |
cytochrome c oxidase subunit 8A |
| Synonyms gene: |
COX8 |
| Synonyms gene name: |
cytochrome c oxidase subunit VIII cytochrome c oxidase subunit VIIIA (ubiquitous) |
| Synonyms: |
COX8-2 COX8L VIII-L COX VIII |
| Locus: |
11q13, 1 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
J04823 |
| Entrez gene record: |
1351 |
| Pubmed identfication: |
2543673 2847943 |
| RefSeq identity: |
NM_004074 |
| Classification: |
Mitochondrial complex IV: cytochrome c oxidase subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000167785 |