Long name: |
Biotin Conjugated, Factor VIII B chain Polyclonal Antibody |
Category: |
Conjugated Primary Antibodies |
Conjugation: |
Biotinylated |
Host Organism: |
Rabbit (Oryctolagus cuniculus) |
Target Antigen: |
Factor VIII B chain |
Specificity: |
This is a highly specific antibody against Factor VIII B chain |
Modification: |
Unmodified |
Modification site: |
None |
Clonality: |
Polyclonal |
Clone: |
Polyclonal antibody |
Concentration: |
1ug per 1ul |
Source: |
KLH conjugated synthetic peptide derived from human Factor VIII B chain |
Gene ID number: |
2157 |
Tested applications: |
IHC-P |
Recommended dilutions: |
IHC-P(1:100-500) |
Crossreactivity: |
Human |
Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
Antigen background: |
Defects in this gene results in hemophilia A, Jul 2008], This binding domain is essential for coagulant activity, This gene produces two alternatively spliced transcripts, This protein undergoes multiple cleavage events, Transcript variant 1 encodes a large glycoprotein, Transcript variant 2 encodes a putative small protein, [provided by RefSeq, a common recessive X-linked coagulation disorder, converts factor X to the activated form Xa, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, isoform a, isoform b, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex, which consists primarily of the phospholipid binding domain of factor VIIIc, which participates in the intrinsic pathway of blood coagulation, This gene encodes coagulation factor VIII |
Purification method: |
This antibody was purified via Protein A |
Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
Synonyms: |
COX8-2 COX8L VIII-L COX VIII |
Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
Gene target: |
Factor VIII B chain Conjugated |
Short name: |
Conjugated, Factor VIII B chain Antibody |
Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
Label: |
Biotin |
Alternative name: |
biotinilated coupled, Factor VIII B epitope (Antibody to) |
Alternative technique: |
antibodies |
Identity: |
2294 |
Gene: |
COX8A |
More about : COX8A |
Long gene name: |
cytochrome c oxidase subunit 8A |
Synonyms gene: |
COX8 |
Synonyms gene name: |
cytochrome c oxidase subunit VIII cytochrome c oxidase subunit VIIIA (ubiquitous) |
Locus: |
11q13, 1 |
Discovery year: |
1989-06-30 |
GenBank acession: |
J04823 |
Entrez gene record: |
1351 |
Pubmed identfication: |
2543673 2847943 |
RefSeq identity: |
NM_004074 |
Classification: |
Mitochondrial complex IV: cytochrome c oxidase subunits |
Havana BLAST/BLAT: |
OTTHUMG00000167785 |