| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Factor VIII B chain |
| Specificity: |
This antibody reacts specifically with Factor VIII B chain |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Factor VIII B chain |
| Gene ID: |
2157 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Defects in this gene results in hemophilia A, Jul 2008], This binding domain is essential for coagulant activity, This gene produces two alternatively spliced transcripts, This protein undergoes multiple cleavage events, Transcript variant 1 encodes a large glycoprotein, Transcript variant 2 encodes a putative small protein, [provided by RefSeq, a common recessive X-linked coagulation disorder, converts factor X to the activated form Xa, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, isoform a, isoform b, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex, which consists primarily of the phospholipid binding domain of factor VIIIc, which participates in the intrinsic pathway of blood coagulation, This gene encodes coagulation factor VIII |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
COX8-2 COX8L VIII-L COX VIII |
| Also known as: |
Factor VIII B chain Polyclonal Antibody |
| Other name: |
Anti-Factor VIII B chain Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Factor VIII B chain |
| Short name: |
Anti-Factor VIII B chain (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Factor VIII B epitope (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2294 |
| Gene: |
COX8A |
More about : COX8A |
| Long gene name: |
cytochrome c oxidase subunit 8A |
| Synonyms gene: |
COX8 |
| Synonyms gene name: |
cytochrome c oxidase subunit VIII cytochrome c oxidase subunit VIIIA (ubiquitous) |
| Locus: |
11q13, 1 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
J04823 |
| Entrez gene record: |
1351 |
| Pubmed identfication: |
2543673 2847943 |
| RefSeq identity: |
NM_004074 |
| Classification: |
Mitochondrial complex IV: cytochrome c oxidase subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000167785 |