| Long name: |
FITC Conjugated, Smad1 (Ser463) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Smad1 Ser463 |
| Specificity: |
This is a highly specific antibody against Smad1 Ser463 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser463 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Smad1 around the phosphorylation site of Ser463 |
| Gene ID number: |
4086 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Alternatively spliced transcript variants encoding the same protein have been observed, In response to BMP ligands, SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways, The phosphorylated form of this protein forms a complex with SMAD4, This protein is a target for SMAD-specific E3 ubiquitin ligases, This protein mediates the signals of the bone morphogenetic proteins (BMPs), [provided by RefSeq], a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C, and undergoes ubiquitination and proteasome-mediated degradation, apoptosis, development and immune responses, elegans gene Sma, morphogenesis, such as SMURF1 and SMURF2, this protein can be phosphorylated and activated by the BMP receptor kinase, which are involved in a range of biological activities including cell growth, which is important for its function in the transcription regulation, The protein encoded by this gene belongs to the SMAD |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
BSP 1, BSP-1, BSP1, Dwarfin A, DwfA, JV 41, JV4 1, JV4-1, JV41, MAD homolog 1, MAD mothers against decapentaplegic homolog 1, MADH 1, MADH1, MADR1, Mad related protein 1, Mad-related protein 1, Madr 1, Mothers against DPP homolog 1, Mothers against DPP homolog 1, Mothers against decapentaplegic homolog 1, Mothers against decapentaplegic homolog 1, SMAD 1, SMAD family member 1, SMAD family member 1, SMAD mothers against DPP homolog 1 Drosophila, SMAD-1, SMAD1_HUMAN, Sma and Mad related protein 1, Smad1, Smad1 phospho Ser463, Spinal muscular atrophy distal with upper limb predominance, TGF beta signaling protein 1, Transforming growth factor beta signaling protein 1, Transforming growth factor-beta-signaling protein 1, hSMAD 1, hSMAD1, p-Smad1 Ser463, Smad1 phospho S463 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Smad1 (Ser463) Conjugated |
| Short name: |
FITC Conjugated, Smad1 (Ser463) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SMAD family member 1 (Ser463) (Antibody to) |
| Alternative technique: |
antibodies |