| Long name: |
ALEXA FLUOR 350 Conjugated, Smad1/5 (Ser463 + Ser465) Antibody |
| Also known as: |
Anti-Smad1/5 Ser463 + Ser465 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Smad1/5 Ser463 + Ser465 |
| Specificity: |
This is a highly specific antibody against Smad1/5 Ser463 + Ser465 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser463 + Ser465 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
440-465/465 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Smad1/5 around the phosphorylation site of Ser463/465 |
| Gene ID Number: |
4086, 4090 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Alternatively spliced transcript variants encoding the same protein have been observed, In response to BMP ligands, SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways, The phosphorylated form of this protein forms a complex with SMAD4, This protein is a target for SMAD-specific E3 ubiquitin ligases, This protein mediates the signals of the bone morphogenetic proteins (BMPs), [provided by RefSeq], a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C, and undergoes ubiquitination and proteasome-mediated degradation, apoptosis, development and immune responses, elegans gene Sma, morphogenesis, such as SMURF1 and SMURF2, this protein can be phosphorylated and activated by the BMP receptor kinase, which are involved in a range of biological activities including cell growth, which is important for its function in the transcription regulation, The protein encoded by this gene belongs to the SMAD |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
BSP 1, BSP-1, BSP1, Dwarfin A, DwfA, JV 41, JV4 1, JV4-1, JV41, MAD homolog 1, MAD mothers against decapentaplegic homolog 1, MADH 1, MADH1, MADR1, Mad related protein 1, Mad-related protein 1, Madr 1, Mothers against DPP homolog 1, Mothers against DPP homolog 1, Mothers against decapentaplegic homolog 1, Mothers against decapentaplegic homolog 1, SMAD 1, SMAD family member 1, SMAD family member 1, SMAD mothers against DPP homolog 1 Drosophila, SMAD-1, SMAD1_HUMAN, Sma and Mad related protein 1, Smad1, Smad1 phospho Ser463/465, Spinal muscular atrophy distal with upper limb predominance, TGF beta signaling protein 1, Transforming growth factor beta signaling protein 1, Transforming growth factor-beta-signaling protein 1, hSMAD 1, hSMAD1, p-Smad1 Ser463/465, Smad1 phospho S463/465 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
Smad1/5 (Ser463 + Ser465) |
| Short name: |
Smad1/5 (Ser463 + Ser465) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, SMAD family member 1/5 (Ser463 and Ser465) (Antibody to) |
| Alternative technique: |
antibodies |