| Long name: |
ALEXA FLUOR 488 Conjugated, GADD34 Polyclonal Antibody |
| Also known as: |
Anti-GADD34 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GADD34 |
| Specificity: |
This is a highly specific antibody against GADD34 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
415-450/674 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GADD34 |
| Gene ID Number: |
23645 |
| Swiss Prot: |
O75807 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1, May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15', thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress, Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
GADD34 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the GADD34 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
GADD34 |
| Short name: |
GADD34 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, GADD34 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14375 |
| Gene: |
PPP1R15A |
More about : PPP1R15A |
| Long gene name: |
protein phosphatase 1 regulatory subunit 15A |
| Synonyms gene name: |
protein phosphatase 1, regulatory (inhibitor) subunit 15A protein phosphatase 1, regulatory subunit 15A |
| Synonyms name: |
growth arrest and DNA-damage-inducible 34 |
| Locus: |
19q13, 2 |
| Discovery year: |
2001-06-29 |
| GenBank acession: |
U83981 |
| Entrez gene record: |
23645 |
| Pubmed identfication: |
9153226 9413226 |
| RefSeq identity: |
NM_014330 |
| Classification: |
Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000183330 |