| Long name: |
GADD34 Primary Polyclonal Antibody |
| Also known as: |
GADD34 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GADD34 |
| Specificity: |
This is a highly specific antibody against GADD34 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
415-450/674 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GADD34 |
| Gene ID number: |
23645 |
| Swiss Prot: |
O75807 |
| Tested Applications: |
IF(IHC-P), IHC-P, FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), FCM(1:20-100) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1, May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15', thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress, Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Growth arrest and DNA damage-inducible protein GADD34, Myeloid differentiation primary response protein MyD116 homolog, PPP1R15A, Protein phosphatase 1 regulatory subunit 15A, GADD34 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GADD34 |
| Short name: |
GADD34 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GADD34 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14375 |
| Gene: |
PPP1R15A |
More about : PPP1R15A |
| Long gene name: |
protein phosphatase 1 regulatory subunit 15A |
| Synonyms gene name: |
protein phosphatase 1, regulatory (inhibitor) subunit 15A protein phosphatase 1, regulatory subunit 15A |
| Synonyms: |
GADD34 |
| Synonyms name: |
growth arrest and DNA-damage-inducible 34 |
| Locus: |
19q13, 2 |
| Discovery year: |
2001-06-29 |
| GenBank acession: |
U83981 |
| Entrez gene record: |
23645 |
| Pubmed identfication: |
9153226 9413226 |
| RefSeq identity: |
NM_014330 |
| Classification: |
Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000183330 |