HSP27 Antibody, Biotin Conjugated

Catalog number:	bs-0730R-Biotin Buy Now
Price:	265 €
Supplier:	MBS Polyclonals
Product name:	HSP27 Antibody, Biotin Conjugated
Quantity:	0.06 ml
Related search:	hsp antibody antibodies shock proteins small stress filaments

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Long name:	Biotin Conjugated, HSP27 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	HSP27
Specificity:	This is a highly specific antibody against HSP27
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	100-150/205
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic peptide derived from human HSP27
Gene ID number:	3315
Swiss Prot:	P04792
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	A major function of these proteins is to serve as chaperones that bind to and stabilize the active conformation of other proteins, Akt (PKB), Another complex consists of HSP27 and the IKK complex, Cytoplasmic HSP27 exists in multiple complexes, HSP27, HSP27 is also an actin capping protein that binds to the barbed (growing) ends of actin filaments, HSP27 is localized to the cytoplasm of unstressed cells but can redistribute to the nucleus in response to stress, MAPKAP-kinase 2, One complex consists of HSP27, Phosphorylation of HSP27 on serine 82 by MAPKAP-kinase 2 leads to HSP27 dissociation from the Akt/MAPKAP-kinase 2/p38 complex and from actin filaments, The presence of HSP27 in this complex is required for Akt activation by stress stimuli, along with other members of the small HSP group, and p38 MAPK, and stimulates HSP27 binding to the IKK complex, possesses a C-terminal Alpha-crystalline homology domain, thereby inhibiting filament extension, where it may function to stabilize DNA and/or the nuclear membrane, Heat Shock Protein 27 (HSP27) is a 27 kDa member of a family of proteins whose expression and function are stimulated by heat shock and other stress stimuli
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	HSP27 HSP28 Hs, 76067 Hsp25 CMT2F
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	HSP27 Conjugated
Short name:	Conjugated, HSP27 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, HSP27 (Antibody to)
Alternative technique:	antibodies
Identity:	5246
Gene:	HSPB1 | More about : HSPB1
Long gene name:	heat shock protein family B (small) member 1
Synonyms gene name:	heat shock 27kD protein 1 heat shock 27kDa protein 1
Locus:	7q11, 23
Discovery year:	1991-07-09
GenBank acession:	X54079
Entrez gene record:	3315
Pubmed identfication:	2243808 9344682
Classification:	Small heat shock proteins
Havana BLAST/BLAT:	OTTHUMG00000023228
Locus Specific Databases:	Inherited Peripheral Neuropathies Mutation Database LRG_248

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• #antibody
• #antibodies
• #shock
• #proteins
• #small
• #stress
• #filaments