JNK1 + 3 Antibody, FITC Conjugated

Catalog number:	bs-0501R-FITC Buy Now
Price:	529 €
Supplier:	acr
Product name:	JNK1 + 3 Antibody, FITC Conjugated
Quantity:	0,1 ml
Related search:	jnk antibody antibodies gene kinase this cell fluorescent proliferation

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Long name:	FITC Conjugated, JNK1 + 3 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Anti-FITC Antibody
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	JNK1 + 3
Specificity:	This is a highly specific antibody against JNK1 + 3
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	270-320/384
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic peptide derived from human JNK1
Gene ID number:	5599
Swiss Prot:	P45983
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Dog, Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Four alternatively spliced transcript variants encoding distinct isoforms have been reported, MAP kinases act as an integration point for multiple biochemical signals, MAP2K4 and MAP2K7, Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, The JNK pathway is critically involved in diabetes and levels are abnormally elevated in obesity, The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis, The cell-permeable JNK inhibitory peptide may have promise as a therapeutic agent for diabetes, This kinase is activated by various cell stimuli, This kinase is also involved in UV radiation induced apoptosis, and are involved in a wide variety of cellular processes such as proliferation, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli, apoptosis and differentiation, differentiation, transcription regulation and development, which is thought to be related to cytochrome c-mediated cell death pathway, JNK1 is activated by threonine and tyrosine phosphorylation by either of two dual specificity kinases, JNK1(MAPK8) is a member of the MAP kinase family
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	494nm/518nm
Synonyms:	JNK JNK1 SAPK1
Properties:	Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	JNK1 + 3 Conjugated
Short name:	FITC Conjugated, JNK1 + 3 Antibody
Technique:	Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	FITC
Alternative name:	fluorecein coupled, JNK1 and 3 (Antibody to)
Alternative technique:	antibodies
Identity:	6881
Gene:	MAPK8 | More about : MAPK8
Long gene name:	mitogen-activated protein kinase 8
Synonyms gene:	PRKM8
Synonyms name:	JUN N-terminal kinase
Locus:	10q11, 22
Discovery year:	1998-04-28
GenBank acession:	L26318
Entrez gene record:	5599
Pubmed identfication:	8137421 8654373
Classification:	Mitogen-activated protein kinases
Havana BLAST/BLAT:	OTTHUMG00000018172

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