JNK1+2+3 Antibody, FITC Conjugated

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Catalog number: bs-2592R-FITC
Price: 529 €
Supplier: acr
Product name: JNK1+2+3 Antibody, FITC Conjugated
Quantity: 0,1 ml
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Long name: FITC Conjugated, JNK1+2+3 Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Anti-FITC Antibody
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: JNK1+2+3
Specificity: This is a highly specific antibody against JNK1+2+3
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen_range: 160-210/384
Subcellular location: Nucleus, Cytoplasm
Source: KLH conjugated synthetic peptide derived from mouse JNK1/2/3
Gene ID number: 264192642026414
Swiss Prot: Q61831
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: Acts in the regulation of the beta-amyloid precursor protein/APP signaling during neuronal differentiation by phosphorylating APP, Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway, In this cascade, In turn, MAPK1/JNK3 phosphorylates a number of transcription factors, Participates also in neurite growth in spiral ganglion neurons, Phosphorylates the neuronal microtubule regulator STMN2, Plays regulatory roles in the signaling pathways during neuronal apoptosis, differentiation, migration and programmed cell death, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK1/JNK3, Serine/threonine-protein kinase involved in various processes such as neuronal proliferation
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission: 494nm/518nm
Synonyms: JNK JNK1 SAPK1
Properties: Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target: JNK1+2+3 Conjugated
Short name: FITC Conjugated, JNK1+2+3 Antibody
Technique: Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: FITC
Alternative name: fluorecein coupled, JNK1+2+3 (Antibody to)
Alternative technique: antibodies
Identity: 6881
Gene: MAPK8 | More about : MAPK8
Long gene name: mitogen-activated protein kinase 8
Synonyms gene: PRKM8
Synonyms name: JUN N-terminal kinase
Locus: 10q11, 22
Discovery year: 1998-04-28
GenBank acession: L26318
Entrez gene record: 5599
Pubmed identfication: 8137421 8654373
Classification: Mitogen-activated protein kinases
Havana BLAST/BLAT: OTTHUMG00000018172

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