JNK1+2+3 Antibody, Biotin Conjugated

Catalog number:	bs-2592R-Biotin Buy Now
Price:	529 €
Supplier:	acr
Product name:	JNK1+2+3 Antibody, Biotin Conjugated
Quantity:	0,1 ml
Related search:	antibody antibodies gene kinase synonyms year

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Long name:	Biotin Conjugated, JNK1+2+3 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	JNK1+2+3
Specificity:	This is a highly specific antibody against JNK1+2+3
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	160-210/384
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic peptide derived from mouse JNK1/2/3
Gene ID number:	264192642026414
Swiss Prot:	Q61831
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Acts in the regulation of the beta-amyloid precursor protein/APP signaling during neuronal differentiation by phosphorylating APP, Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway, In this cascade, In turn, MAPK1/JNK3 phosphorylates a number of transcription factors, Participates also in neurite growth in spiral ganglion neurons, Phosphorylates the neuronal microtubule regulator STMN2, Plays regulatory roles in the signaling pathways during neuronal apoptosis, differentiation, migration and programmed cell death, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK1/JNK3, Serine/threonine-protein kinase involved in various processes such as neuronal proliferation
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	JNK JNK1 SAPK1
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	JNK1+2+3 Conjugated
Short name:	Conjugated, JNK1+2+3 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, JNK1+2+3 (Antibody to)
Alternative technique:	antibodies
Identity:	6881
Gene:	MAPK8 | More about : MAPK8
Long gene name:	mitogen-activated protein kinase 8
Synonyms gene:	PRKM8
Synonyms name:	JUN N-terminal kinase
Locus:	10q11, 22
Discovery year:	1998-04-28
GenBank acession:	L26318
Entrez gene record:	5599
Pubmed identfication:	8137421 8654373
Classification:	Mitogen-activated protein kinases
Havana BLAST/BLAT:	OTTHUMG00000018172

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