| Catalog number: | bs-0501R-A555 |
|---|---|
| Price: | 558 € |
| Supplier: | acr |
| Product name: | JNK1 + 3 Antibody, ALEXA FLUOR 555 |
| Quantity: | 0,1 mg |
| Related search: |
| Long name: | ALEXA FLUOR 555 Conjugated, JNK1 + 3 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-JNK1 + 3 PAb ALEXA FLUOR 555 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 555, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | JNK1 + 3 |
| Specificity: | This is a highly specific antibody against JNK1 + 3 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 270-320/384 |
| Subcellular location: | Nucleus, Cytoplasm |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human JNK1 |
| Gene ID Number: | 5599 |
| Swiss Prot: | P45983 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Dog, Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Four alternatively spliced transcript variants encoding distinct isoforms have been reported, MAP kinases act as an integration point for multiple biochemical signals, MAP2K4 and MAP2K7, Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, The JNK pathway is critically involved in diabetes and levels are abnormally elevated in obesity, The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis, The cell-permeable JNK inhibitory peptide may have promise as a therapeutic agent for diabetes, This kinase is activated by various cell stimuli, This kinase is also involved in UV radiation induced apoptosis, and are involved in a wide variety of cellular processes such as proliferation, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli, apoptosis and differentiation, differentiation, transcription regulation and development, which is thought to be related to cytochrome c-mediated cell death pathway, JNK1 is activated by threonine and tyrosine phosphorylation by either of two dual specificity kinases, JNK1(MAPK8) is a member of the MAP kinase family |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 553nm/568nm |
| Synonyms: | JNK JNK1 SAPK1 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 555, Alexa Fluor |
| Gene target: | JNK1 + 3 |
| Short name: | JNK1 + 3 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 555 |
| Alternative name: | ALEXA FLUOR 555, JNK1 and 3 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 6881 |
| Gene: | MAPK8 | More about : MAPK8 |
| Long gene name: | mitogen-activated protein kinase 8 |
| Synonyms gene: | PRKM8 |
| Synonyms name: | JUN N-terminal kinase |
| Locus: | 10q11, 22 |
| Discovery year: | 1998-04-28 |
| GenBank acession: | L26318 |
| Entrez gene record: | 5599 |
| Pubmed identfication: | 8137421 8654373 |
| Classification: | Mitogen-activated protein kinases |
| Havana BLAST/BLAT: | OTTHUMG00000018172 |
| MBS616079 | JNK1/2, phosphorylated (Thr183, Tyr185) (c-Jun N-terminal Kinase 1, JNK1, JNK, c-Jun N-terminal Kinase 2, JNK2, JNK1A2, JNK21B1/2, JNK-46, JNK-55, Mitogen-activated Protein Kinase 8, MAP Kinase 8, MAPK 8, MAPK8, PRKM8, Mitogen-activated Protein Kinase 9, Antibody | 10 Blots | 663 € | MBS Polyclonals_1 | human |
| MBS611557 | JNK1 (Jun Kinase 1, c-Jun N-terminal Kinase, Stress Activated Protein Kinase alpha, SAPKa, JAK1A, JNK46, JNK1 alpha 2, JNK21B1/2, Mitogen Activated Protein Kinase 8, MAPK8, MK08, p54 gamma, PRKM8) Antibody | 100ul | 597 € | MBS Polyclonals_1 | human |
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