| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
JNK1 + 2 + 3 (THR183+TYR185) |
| Specificity: |
This antibody reacts specifically with JNK1+2+3 (THR183+TYR185) |
| Modification: |
Phosphorylation |
| Modification site: |
THR183+TYR185 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Thr183/Tyr185 |
| Gene ID: |
5599 |
| Swiss Prot: |
P45983 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Bovine, Dog, Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
However, alpha-2, and beta-2 have a similar low level of binding to both c-Jun or ATF2, there is no correlation between binding and phosphorylation, whereas alpha-1, which is achieved at about the same efficiency by all isoforms, JNK1 isoforms display different binding patterns: beta-1 preferentially binds to c-Jun |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
JNK JNK1 SAPK1 |
| Also known as: |
JNK1+2+3 (THR183+TYR185) |
| Other name: |
Anti-JNK1+2+3 (THR183+TYR185) |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
JNK1+2+3 (THR183+TYR185) |
| Short name: |
Anti-JNK1+2+3 (THR183+TYR185) Fluor 594 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-JNK1+2+3 (THR183+TYR185) |
| Identity: |
6881 |
| Gene: |
MAPK8 |
More about : MAPK8 |
| Long gene name: |
mitogen-activated protein kinase 8 |
| Synonyms gene: |
PRKM8 |
| Synonyms name: |
JUN N-terminal kinase |
| Locus: |
10q11, 22 |
| Discovery year: |
1998-04-28 |
| GenBank acession: |
L26318 |
| Entrez gene record: |
5599 |
| Pubmed identfication: |
8137421 8654373 |
| Classification: |
Mitogen-activated protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000018172 |