JNK1+2+3 Antibody, ALEXA FLUOR 488

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Catalog number: bs-2592R-A488
Price: 558 €
Supplier: acr
Product name: JNK1+2+3 Antibody, ALEXA FLUOR 488
Quantity: 0,1 mg
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Long name: ALEXA FLUOR 488 Conjugated, JNK1+2+3 Polyclonal Antibody
Also known as: Anti-JNK1+2+3 PAb ALEXA FLUOR 488
Category: Conjugated Primary Antibodies
Conjugated with: 488, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: JNK1+2+3
Specificity: This is a highly specific antibody against JNK1+2+3
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 160-210/384
Subcellular location: Nucleus, Cytoplasm
Source: KLH conjugated synthetic peptide derived from mouse JNK1/2/3
Gene ID Number: 264192642026414
Swiss Prot: Q61831
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: Acts in the regulation of the beta-amyloid precursor protein/APP signaling during neuronal differentiation by phosphorylating APP, Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway, In this cascade, In turn, MAPK1/JNK3 phosphorylates a number of transcription factors, Participates also in neurite growth in spiral ganglion neurons, Phosphorylates the neuronal microtubule regulator STMN2, Plays regulatory roles in the signaling pathways during neuronal apoptosis, differentiation, migration and programmed cell death, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK1/JNK3, Serine/threonine-protein kinase involved in various processes such as neuronal proliferation
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 499nm/519nm
Synonyms: JNK JNK1 SAPK1
Properties: ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the JNK1+2+3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: Alexa Fluor
Gene target: JNK1+2+3
Short name: JNK1+2+3 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 488
Alternative name: ALEXA FLUOR 488, JNK1+2+3 (Antibody to)
Alternative technique: antibodies
Identity: 6881
Gene: MAPK8 | More about : MAPK8
Long gene name: mitogen-activated protein kinase 8
Synonyms gene: PRKM8
Synonyms name: JUN N-terminal kinase
Locus: 10q11, 22
Discovery year: 1998-04-28
GenBank acession: L26318
Entrez gene record: 5599
Pubmed identfication: 8137421 8654373
Classification: Mitogen-activated protein kinases
Havana BLAST/BLAT: OTTHUMG00000018172

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