| Long name: |
FITC Conjugated, OPG Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
OPG |
| Specificity: |
This is a highly specific antibody against OPG |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
235-280/401 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from mouse OPG |
| Gene ID number: |
18383 |
| Swiss Prot: |
O08712 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B, Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro, May act as decoy receptor for TNFSF1/TRAIL and protect against apoptosis, May also play a role in preventing arterial calcification, TNFSF1/TRAIL binding blocks the inhibition of osteoclastogenesis, Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
OCIF TR1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
OPG Conjugated |
| Short name: |
FITC Conjugated, OPG Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, OPG (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11909 |
| Gene: |
TNFRSF11B |
More about : TNFRSF11B |
| Long gene name: |
TNF receptor superfamily member 11b |
| Synonyms gene: |
OPG |
| Synonyms gene name: |
member 11b , osteoprotegerin tumor necrosis factor receptor superfamily |
| Locus: |
8q24, 12 |
| Discovery year: |
1997-09-05 |
| GenBank acession: |
U94332 |
| Entrez gene record: |
4982 |
| Pubmed identfication: |
9108485 |
| Classification: |
Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000164969 |