| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Osteoprotegerin (OPG) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IF, IHC, WB |
| Recommended dilutions: |
IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: |
Titration of the OPG antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This OPG antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O00300 |
| Purity: |
Antigen affinity |
| Description: |
Alternatively spliced transcript variants of this gene have been reported, Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification, This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption, This protein specifically binds to its ligand, both of which are key extracellular regulators of osteoclast development, but their full length nature has not been determined, osteoprotegerin ligand, The protein encoded by this gene is a member of the TNF-receptor superfamily |
| Immunogen: |
A portion of amino acids 243-271 from the human protein was used as the immunogen for this OPG antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the OPG antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Osteoprotegerin (OPG) |
| Short name: |
Osteoprotegerin Antibody (OPG) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Osteoprotegerin (Antibody to) (OPG) |
| Alternative technique: |
antibodies |
| Identity: |
11909 |
| Gene: |
TNFRSF11B |
More about : TNFRSF11B |
| Long gene name: |
TNF receptor superfamily member 11b |
| Synonyms gene: |
OPG |
| Synonyms gene name: |
member 11b , osteoprotegerin tumor necrosis factor receptor superfamily |
| Synonyms: |
OCIF TR1 |
| Locus: |
8q24, 12 |
| Discovery year: |
1997-09-05 |
| GenBank acession: |
U94332 |
| Entrez gene record: |
4982 |
| Pubmed identfication: |
9108485 |
| Classification: |
Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000164969 |