| Long name: |
ALEXA FLUOR 647 Conjugated, WNK4 Polyclonal Antibody |
| Also known as: |
Anti-WNK4 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
WNK4 |
| Specificity: |
This is a highly specific antibody against WNK4 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human WNK4 |
| Gene ID Number: |
65266 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Also inhibits the renal K(+)channel, KCNJ1, SLC12A3, WNK4 appears to act as a molecular switch that can vary the balance between NaCl reabsorption and K(+)secretion to maintain integrated homeostasis, by phosphorylation which appears to prevent membrane trafficking of SLC12A3, via a kinase-independent mechanism by which it induces clearance of the protein from the cell surface by clathrin-dependent endocytosis, Regulates the activity of the thiazide-sensitive Na-Cl cotransporter |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the WNK4 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
WNK4 |
| Short name: |
WNK4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, WNK lysine deficient protein kinase 4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cell surfaces, WNK4 and IDBG-51675 and ENSG00000126562 and 102724304, WNK4 and IDBG-640438 and ENSBTAG00000019907 and 100849076, Wnk4 and IDBG-211994 and ENSMUSG00000035112 and 69847, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005923 and tight junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006811 and ion transport and biological process this GO :0006821 and chloride transport and biological process this GO :0008104 and protein localization and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0019869 : chloride channel inhibitor activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019869 : chloride channel inhibitor activity, transferring phosphorus-containing groups and molecular function this GO :0019869 and chloride channel inhibitor activity and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0050794 and regulation of cellular process and biological process this GO :0050801 and ion homeostasis and biological process this GO :0070294 and renal sodium ion absorption and biological process this GO :0072156 and distal tubule morphogenesis and biological process this GO :0090188 and negative regulation of pancreatic juice secretion and biological process, 65266, WNK lysine deficient protein kinase 4 |
| Identity: |
14544 |
| Gene: |
WNK4 |
More about : WNK4 |
| Long gene name: |
WNK lysine deficient protein kinase 4 |
| Synonyms gene: |
PRKWNK4 |
| Synonyms gene name: |
lysine deficient 4 , protein kinase |
| Locus: |
17q21, 2 |
| Discovery year: |
2001-02-07 |
| GenBank acession: |
AJ309861 |
| Entrez gene record: |
65266 |
| Havana BLAST/BLAT: |
OTTHUMG00000180650 |