| Long name: |
C5a anaphylatoxin Primary Polyclonal Antibody |
| Also known as: |
C5a anaphylatoxin PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
C5a anaphylatoxin |
| Specificity: |
This is a highly specific antibody against C5a anaphylatoxin |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
700-755/1680 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from mouse C5a (725-770aa) |
| Gene ID number: |
15139 |
| Swiss Prot: |
P06684 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, C5 anaphylatoxin is a mediator of local inflammatory process, C5-C9, C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation, C5b has a transient binding site for C6, Derived from proteolytic degradation of complement C5, The C5b-C6 complex is the foundation upon which the lytic complex is assembled, and histamine release from mast cells and basophilic leukocytes, contraction of smooth muscle, increased vascular permeability, into the membrane attack complex, Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
C5a, Complement C5, Hc, He, Hemolytic complement, C5 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
C5a anaphylatoxin |
| Short name: |
C5a anaphylatoxin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
C5a anaphylatoxin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1331 |
| Gene: |
C5 |
More about : C5 |
| Long gene name: |
complement C5 |
| Synonyms gene name: |
complement component 5 |
| Synonyms: |
CPAMD4 C5a C5b |
| Synonyms name: |
prepro-C5 C5a anaphylatoxin |
| Locus: |
9q33, 2 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M57729 |
| Entrez gene record: |
727 |
| RefSeq identity: |
NM_001735 |
| Classification: |
Endogenous ligands Complement system C3 and PZP like, alpha-2-macroglobulin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000020579 |
| Locus Specific Databases: |
C5base: Mutation registry for C5 deficiency LRG_28 |