| Long name: |
ALEXA FLUOR 647 Conjugated, C5a anaphylatoxin Polyclonal Antibody |
| Also known as: |
Anti-C5a anaphylatoxin PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
C5a anaphylatoxin |
| Specificity: |
This is a highly specific antibody against C5a anaphylatoxin |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
700-755/1680 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from mouse C5a (725-770aa) |
| Gene ID Number: |
15139 |
| Swiss Prot: |
P06684 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, C5 anaphylatoxin is a mediator of local inflammatory process, C5-C9, C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation, C5b has a transient binding site for C6, Derived from proteolytic degradation of complement C5, The C5b-C6 complex is the foundation upon which the lytic complex is assembled, and histamine release from mast cells and basophilic leukocytes, contraction of smooth muscle, increased vascular permeability, into the membrane attack complex, Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
CPAMD4 C5a C5b |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the C5a anaphylatoxin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
C5a anaphylatoxin |
| Short name: |
C5a anaphylatoxin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, C5a anaphylatoxin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1331 |
| Gene: |
C5 |
More about : C5 |
| Long gene name: |
complement C5 |
| Synonyms gene name: |
complement component 5 |
| Synonyms name: |
prepro-C5 C5a anaphylatoxin |
| Locus: |
9q33, 2 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M57729 |
| Entrez gene record: |
727 |
| RefSeq identity: |
NM_001735 |
| Classification: |
Endogenous ligands Complement system C3 and PZP like, alpha-2-macroglobulin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000020579 |
| Locus Specific Databases: |
C5base: Mutation registry for C5 deficiency LRG_28 |