| Long name: |
ALEXA FLUOR 594 Conjugated, APAF1 Polyclonal Antibody |
| Also known as: |
Anti-APAF1CT PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
APAF1CT |
| Specificity: |
This is a highly specific antibody against APAF1CT |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1200-1248/1248 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Apaf-1 |
| Gene ID Number: |
317 |
| Swiss Prot: |
O14727 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Isoform 6 is less effective in inducing apoptosis, This activation requires ATP, leading to the activation of caspase-3 and apoptosis, Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CED4 APAF-1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
APAF1 |
| Short name: |
APAF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, apoptotic peptidase activating factor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ADP binding, APAF-1 and CED4, APAF1 and IDBG-52364 and ENSG00000120868 and 317, APAF1 and IDBG-636787 and ENSBTAG00000021661 and 537782, Apaf1 and IDBG-185032 and ENSMUSG00000019979 and 11783, nuclei, this GO :0000166 and nucleotide binding and molecular function this GO :0001843 and neural tube closure and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006952 and defense response and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007399 and nervous system development and biological process this GO :0007420 and brain development and biological process this GO :0008635 and activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0030900 and forebrain development and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043293 and apoptosome and cellular component this GO :0043531 and ADP binding and molecular function this GO :0051402 and neuron apoptotic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072432 and response to G1 DNA damage checkpoint signaling and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :1902510 and regulation of apoptotic DNA fragmentation and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, this GO :0000166 : nucleotide binding, this GO :0000166 : nucleotide binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process and also this GO :0042802 : identical protein binding and also this GO :0043531 : ADP binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0042802 : identical protein binding, this GO :0043531 : ADP binding, apoptotic peptidase activating factor 1 |
| Identity: |
576 |
| Gene: |
APAF1 |
More about : APAF1 |
| Long gene name: |
apoptotic peptidase activating factor 1 |
| Synonyms gene name: |
apoptotic protease activating factor apoptotic peptidase activating factor |
| Locus: |
12q23, 1 |
| Discovery year: |
1998-01-20 |
| GenBank acession: |
AF013263 |
| Entrez gene record: |
317 |
| Pubmed identfication: |
9267021 10702682 |
| RefSeq identity: |
NM_181861, 1 |
| Classification: |
Caspase recruitment domain containing Apoptosome WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000170214 |