| Long name: |
ALEXA FLUOR 488 Conjugated, Apaf1 Interacting Protein Antibody |
| Also known as: |
Anti-Apaf1 Interacting Protein PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Apaf1 Interacting Protein |
| Specificity: |
This is a highly specific antibody against Apaf1 Interacting Protein |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APIP |
| Gene ID Number: |
51074 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A new Apaf1 Interacting Protein (APIP) also known as CG129 and MMRP19, APIP competes with Caspase 9 binding site of Apaf1, APIP is predicted to code for a 204 amino acid, APIP transcript is ubiquitously expressed in most adult tissue with high expression in skeletal muscle, APIP2 encodes a 242 amino acid protein, Activated caspase 9 in turn cleaves and activates caspase 3 that is one of the key proteases, An isoform of APIP, Apaf1 binds to cytochrome c (Apaf2) and caspase 9 (Apaf3), and kidney, being responsible for the proteolytic cleavage of many key proteins in apoptosis, elegans has been identified recently from human and mouse and designated Apaf1 (for apoptosis protease activating factor 1), has been identified as a negative regulator of ischemic injury, heart, which is an alternative splicing variant differing in its N terminus from APIP, which leads to caspase 9 activation, The mammalian homologues of the key cell death gene CED 4 in C |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
CGI-29 Mmrp19 APIP2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Apaf1 Interacting Protein Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Apaf1 Interacting Protein |
| Short name: |
Apaf1 Interacting Protein Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, apoptotic peptidase activating factor 1 Interacting Protein (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17581 |
| Gene: |
APIP |
More about : APIP |
| Long gene name: |
APAF1 interacting protein |
| Synonyms name: |
methylthioribulose-1-phosphate dehydratase |
| Locus: |
11p13 |
| Discovery year: |
2005-11-10 |
| GenBank acession: |
AF132963 |
| Entrez gene record: |
51074 |
| Pubmed identfication: |
10810093 15262985 24367089 |
| RefSeq identity: |
NM_015957 |
| Havana BLAST/BLAT: |
OTTHUMG00000166455 |