presenilin 1 Antibody, ALEXA FLUOR 594

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Catalog number: bs-0025M-A594
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: presenilin 1 Antibody, ALEXA FLUOR 594
Quantity: 100ul
Other quantities: 100ul 332€
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Long name: ALEXA FLUOR 594 Conjugated, presenilin 1 Polyclonal Antibody
Also known as: Anti-presenilin 1 PAb ALEXA FLUOR 594
Category: Conjugated Primary Antibodies
Conjugated with: 594, ALEXA FLUOR®
Host Organism: Mouse (Mus musculus)
Target Antigen: presenilin 1
Specificity: This is a highly specific antibody against presenilin 1
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 250-300/467
Subcellular location: Cytoplasm
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Presenilin-1 CTF subunit
Gene ID Number: 19164
Swiss Prot: P49769
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Rabbit, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: May also play a role in hematopoiesis (By similarity), May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane, Requires the other members of the gamma-secretase complex to have a protease activity, Stimulates cell-cell adhesion though its association with the E-cadherin/catenin complex, Under conditions of apoptosis or calcium influx, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein), cleaves E-cadherin promoting the disassembly of the E-cadherin/catenin complex and increasing the pool of cytoplasmic beta-catenin, thus negatively regulating Wnt signaling, Probable catalytic subunit of the gamma-secretase complex
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 590nm/617nm
Synonyms: PRO2207 PSARL1 RHBDS1
Properties: ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: 594, ALEXA FLUOR®, Alexa Fluor
Conjugated: Alexa conjugate 1
Gene target: presenilin 1
Short name: presenilin 1 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 594
Alternative name: ALEXA FLUOR 594, presenilin 1 (Antibody to)
Alternative technique: antibodies
Identity: 18253
Gene: PARL | More about : PARL
Long gene name: presenilin associated rhomboid like
Synonyms gene: PSARL
Synonyms gene name: presenilin associated, rhomboid-like
Synonyms name: rhomboid 7 homolog 1 (Drosophila)
Locus: 3q27, 1
Discovery year: 2003-09-03
GenBank acession: AF116692
Entrez gene record: 55486
RefSeq identity: NM_018622
Classification: Rhomboid family
Havana BLAST/BLAT: OTTHUMG00000156890

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