| Long name: |
ALEXA FLUOR 555 Conjugated, presenilin 1 Polyclonal Antibody |
| Also known as: |
Anti-presenilin 1 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Mouse (Mus musculus) |
| Target Antigen: |
presenilin 1 |
| Specificity: |
This is a highly specific antibody against presenilin 1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1-50/467 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from rat presenilin 1 |
| Gene ID Number: |
29192 |
| Swiss Prot: |
P97887 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rabbit, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
May also play a role in hematopoiesis (By similarity), May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane, Requires the other members of the gamma-secretase complex to have a protease activity, Stimulates cell-cell adhesion though its association with the E-cadherin/catenin complex, Under conditions of apoptosis or calcium influx, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein), cleaves E-cadherin promoting the disassembly of the E-cadherin/catenin complex and increasing the pool of cytoplasmic beta-catenin, thus negatively regulating Wnt signaling, Probable catalytic subunit of the gamma-secretase complex |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
PRO2207 PSARL1 RHBDS1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
presenilin 1 |
| Short name: |
presenilin 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, presenilin 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18253 |
| Gene: |
PARL |
More about : PARL |
| Long gene name: |
presenilin associated rhomboid like |
| Synonyms gene: |
PSARL |
| Synonyms gene name: |
presenilin associated, rhomboid-like |
| Synonyms name: |
rhomboid 7 homolog 1 (Drosophila) |
| Locus: |
3q27, 1 |
| Discovery year: |
2003-09-03 |
| GenBank acession: |
AF116692 |
| Entrez gene record: |
55486 |
| RefSeq identity: |
NM_018622 |
| Classification: |
Rhomboid family |
| Havana BLAST/BLAT: |
OTTHUMG00000156890 |